March 1, 1980European Journal of BiochemistryOpen Access

Use of Antibodies against Dodecylsulfate-Denatured Heavy Meromyosins to Probe Structural Differences between Muscular Myosin Isoenzymes

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Population

Guinea-pigs immunized with heavy meromyosin purified from rabbit fast twitch muscles and rat cardiac…

Design

Preclinical

Authors

KSKetty SchwartzUniversité Claude Bernard Lyon 1 ALAnne‐Marie LompréHeart Failure / Cardiomyopathy PBP. BouveretCentre de recherche Translationnelle en Médecine moléculaire

Discussion

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Implication

Antibody tools for myosin isoenzyme mapping in animal models; leaves open extension to human cardiac myosin variants.

Structured PICO

Population

Guinea-pigs immunized with heavy meromyosin purified from rabbit fast twitch muscles and rat cardiac ventricles

Intervention

Antibodies against sodium dodecylsulfate-denatured heavy meromyosins

Outcome

Structural differences and antigenic structures of denatured myosins across species and muscle typessurrogate

Antibodies against denatured heavy meromyosin provide a discriminant means for estimating structural relationships between myosin isoenzymes and localizing constant and variable regions in their heavy chains.

Cite This Study

Schwartz et al. (1980) studied this question.

synapsesocial.com/papers/6a8bc9dac716e89f35defa91 https://doi.org/10.1111/j.1432-1033.1980.tb04434.x

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Use of Antibodies against Dodecylsulfate-Denatured Heavy Meromyosins to Probe Structural Differences between Muscular Myosin Isoenzymes

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Use of Antibodies against Dodecylsulfate-Denatured Heavy Meromyosins to Probe Structural Differences between Muscular Myosin Isoenzymes

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider