Identifies a distinct hemodynamic syndrome of spontaneous cyclic severe mitral regurgitation with wide fluctuations in pulmonary capillary wedge pressure V waves.
May represent an intermediate mitral regurgitation phenotype; hypothesis-generating and should not yet change practice.
Two patients are described with spontaneous wide fluctuations in the size of pulmonary capillary wedge pressure V waves thought to be related to cyclic spontaneous variations in the degree of mitral regurgitation over very short periods of time. The findings are thought to represent a hemodynamically distinct syndrome intermediate between chronic severe and acute severe mitral regurgitation.
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Engel et al. (1989) studied this question.
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