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In a combined Danish, American and Icelandic study, the odds for the orientation PGM3 :GLO:HLA-B:HLA-A versus GLO:HLA-B:HLA-A:PGM3 are estimated to be 75:1. The GLO:HLA recombination frequency is estimated at 5% for males and 12% for females. The recombination fraction for PGM3:GLO is 12--13% in males and is significantly higher in females (approximately free recombination). The findings are consistent with the large sex differences in recombination frequency between HLA and PGM3.
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Lamm et al. (1978) studied this question.
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