Why the study?
Does implantable loop recorder placement identify cardiac causes in patients with refractory convulsive episodes misdiagnosed as epilepsy?
Does implantable loop recorder placement identify cardiac causes in patients with refractory convulsive episodes misdiagnosed as epilepsy?
Implantable loop recorders can successfully identify cardiovascular causes like asystole or heart block in patients with refractory convulsive episodes misdiagnosed as epilepsy, allowing for curative pacemaker therapy.
ILR may identify treatable causes in select refractory cases; hypothesis-generating and should not yet change practice.
INTRODUCTION: Not all convulsive episodes are due to epilepsy and a number of these have a cardiovascular cause. Failure to identify these patients delays the provision of adequate therapy while at the same time exposes the individual to the risk of injury or death. METHODS: We report on three patients who suffered from recurrent convulsive episodes, thought to be epileptic in origin, who were refractory to antiseizure therapy. Although each patient had undergone extensive evaluation, no other potential cause of his or her seizure like episodes had been uncovered. In each patient placement of an implantable loop recorder (ILR) demonstrated that their convulsive episodes were due to prolonged periods of cardiac asystole and/or complete heart block. In all patients their convulsive episodes were eliminated by permanent pacemaker implantation. CONCLUSION: In patients with refractory "seizure' like episodes of convulsive activity of unknown etiology a potential cardiac rhythm disturbance should be considered and can be easily evaluated by ILR placement.
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Kanjwal et al. (2009) studied this question.
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