Some aspects of multidimensional chromatographic techniques coupled with mass spectrometry applied for the separation of multicomponent mixtures of pesticides

For very complex multicomponent mixtures, it is preferable to use different variants of multidimensional (planar) chromatography. In multidimensional separations, the modes of planar chromatography commonly applied are comprehensive 2D planar chromatography on mono and bilayers, coupled-layer chromatography, combination of multidimensional planar chromatographic (MDPC) techniques, and also hyphenated methods. Different multidimensional (planar) chromatography techniques and hyphenated methods may be alternative modes for separation and identifcation of pesticides in environmental analysis, especially after coupling with modern detection techniques. Proper identifcation and quantitative analysis of the analytes are possible through the use of sensitive detection techniques such as high-resolution mass spectrometry (HRMS).