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The immune system is the armor of body, which stands against the infection and various diseases. Immune suppression/stimulation may lead to variety of disorders. Immunomodulators help to balance immunity that induces (stimulation) or attenuates (suppression) according to the therapeutic need. From ancient times, natural products have been utilised for the modulation of immune system. Traditional system of medicines such as Ayurveda, Unani, Traditional Chinese medicine (TCM) describes varieties of evidences for the vast pharmacological activity. Some of the major plant-derived compounds potentially explored as immunomodulators i.e. curcumin, resveratrol, epigallocatechin-3-gallate, andrographolide, genistein etc. Present review will provide an overview on plant-derived immunomodulator metabolites and their effects on immune system.
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Shukla et al. (2022) studied this question.
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