Efficacy of Brief Interventions for Comorbid Substance Misuse in Patients on Opioid Agonist Treatment: A Systematic Review and Meta-analysis

Abhishek Ghosh; Sanjana Kathiravan; Pranshu Singh; Babita Sharma; Surabhi Gupta; Renjith R. Pillai

doi:10.1097/adm.0000000000001058

August 24, 2022Journal of Addiction Medicine

Efficacy of Brief Interventions for Comorbid Substance Misuse in Patients on Opioid Agonist Treatment: A Systematic Review and Meta-analysis

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Key Points

To evaluate the efficacy and qualitative implementation of screening and brief interventions for comorbid alcohol and drug misuse among patients receiving opioid agonist treatment.
Systematically searched five electronic databases for published and unpublished clinical trials evaluating screening and brief interventions (SBI) in opioid agonist treatment (OAT) populations.
Identified eight eligible studies, including five in a quantitative meta-analysis to assess standardized mean differences in substance risk scores and daily alcohol consumption.
Brief interventions significantly reduced pre-to-post substance risk scores with a medium effect size (Hedges g = 0.752, 95% CI: 0.405 to 1.099).
Interventions produced modest risk score reductions across both alcohol and illicit drug misuse in patients prescribed methadone or buprenorphine, with significant decreases in daily alcohol consumption at 3 months.
Narrative synthesis revealed that screening for substance misuse and delivery of brief interventions remain limited and inconsistently implemented in routine OAT settings.

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Implication

Systematic review and meta-analysis reveals reduced substance risk scores in patients on opioid agonist treatment, suggesting brief interventions effectively curb comorbid misuse.

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Ghosh et al. (2022) studied this question.

synapsesocial.com/papers/6a8be107df3a83baf8caaf94 https://doi.org/10.1097/adm.0000000000001058

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Efficacy of Brief Interventions for Comorbid Substance Misuse in Patients on Opioid Agonist Treatment: A Systematic Review and Meta-analysis

Key Points

No abstract yet

Implication

Discussion

Cite This Study

Efficacy of Brief Interventions for Comorbid Substance Misuse in Patients on Opioid Agonist Treatment: A Systematic Review and Meta-analysis

Key Points

No abstract yet

Implication

Discussion

Cite This Study

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