Why the study?
Adenovirus infections pose a significant health burden in paediatrics, but diagnosis is challenging due to overlapping symptoms with other infections.
This review highlights the clinical burden of adenovirus in pediatrics and emphasizes the need for accurate molecular diagnosis and supportive management.
May prompt molecular testing in pediatric adenovirus; leaves open prospective validation of strategies.
Adenovirus infections in paediatrics present a significant health burden, causing various respiratory, gastrointestinal and ocular illnesses. Diagnosing adenovirus infections in pediatric patients can be challenging due to overlapping symptoms with other viral and bacterial infections. Molecular techniques, such as polymerase chain reaction, are highly sensitive and specific for adenovirus detection. Enhanced surveillance, accurate diagnosis, supportive management and preventive measures are crucial for reducing the morbidity and mortality associated with adenovirus infections in pediatric populations. Further research is needed to advance our understanding of adenovirus pathogenesis, develop effective antiviral therapies and improve vaccine strategies.
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Doddikoppad et al. (2023) studied this question.
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