Mann & Smithies (1955) showed that the oxidation of 1:4-diaminobutane and 1:5-diaminopentane, catalysed by plant amine oxidase, results in the formation of Al-pyrroline and 2:3:4:5-tetrahydro- pyridine compounds respectively. The ring com- pounds are presumably formed by the spontaneous cyclization of the aldimines which are the probable products of the enzyme-catalysed reactions or of the amine aldehydes subsequently formed by the reaction of the aldimines with water. Plant amine
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Mann et al. (1955) studied this question.
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