Synthesis and Absolute Confifguration of the Enantiomers of Verapamil. Starting from the acids IV‐(+) and IV‐(−), a synthesis of the enantiomers I‐(+) and I‐(−) of the coronary vasodilator Verapamil is described and their absolute configuration determined through a chemical filiation with the acid XII‐(S)‐(+).
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Henri Ramuz (1975) studied this question.
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