Second-site revertants of an inactive T4 lysozyme mutant restore activity by restructuring the active site cleft

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1Structure of a thermostable disulfide-bridge mutant of phage T4 lysozyme shows that an engineered cross-link in a flexible region does not increase the rigidity of the folded protein1990 · 77 citations
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3. 3An efficient general-purpose least-squares refinement program for macromolecular structures1987 · 854 citations
4. 4Purification of Bacteriophage T4 Lysozyme1968 · 225 citations
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