Why the study?
Noncardiogenic pulmonary edema in hunting dogs is uncommon, poorly described, and lacks available preventive treatment.
Does treatment with sympathetic blockers or furosemide prevent recurrent hunting-associated respiratory distress episodes in hunting dogs?
Does treatment with sympathetic blockers or furosemide prevent recurrent hunting-associated respiratory distress episodes in hunting dogs?
Sympathetic blockers or furosemide may be effective in preventing recurrent exercise-induced noncardiogenic pulmonary edema or pulmonary hemorrhage in hunting dogs.
Noncardiogenic pulmonary edema (NCPE) in hunting dogs is an uncommon and poorly described condition for which no preventive treatment is available. Two dogs were presented for recurrent respiratory distress strictly associated with hunting activities. Diagnosis was based on bilateral, symmetrical, interstitial-to-alveolar pattern in the caudodorsal lung fields on thoracic radiographs, exclusion of other causes, and spontaneous clinical and radiographic improvement. Considering that the pathogenesis of exercise-induced NCPE likely involves α- and β-adrenergic overstimulation, treatment with sympathetic blockers was used in both dogs. The first dog no longer showed respiratory signs during hunting activities. However, treatment failed to prevent respiratory distress in the other dog. Based on the large number of red blood cells in the bronchoalveolar lavage fluid of the second dog, exercise-induced pulmonary hemorrhage was suspected, as described in racing horses. The loop diuretic furosemide successfully prevented further hunting-associated respiratory distress episodes in this dog.
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Dumont et al. (2023) studied this question.
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