Selectivity factors: The resolution of tertiary and secondary alcohols, which arise from ketone and aldehyde aldol additions, proceeds in the presence of (1S,2R)-N-methylephedrine (see example). The method is technically simple, easily scalable, and provides tertiary and secondary alcohols in high enantiomeric ratios.
No takes yet. Share an insight, caveat, or question.
Schipper et al. (2009) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: