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The history, clinical findings, and postmortem examination of a patient with Kearns-Sayre syndrome are presented. In addition to the usuual symptoms, the patient also had hypoparathyroidism. There is increasing evidence that the syndrome is frequently associated with involvement ofthe endocrine system. Central nervous system involvement consists of a spongy encephalopathy.
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Horwitz et al. (1978) studied this question.
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