Incomplete Conflicts of Interest Disclosures in: Fish Oil and Postoperative Atrial Fibrillation: The Omega-3 Fatty Acids for Prevention of Post-operative Atrial Fibrillation (OPERA) Randomized Trial

The Kaplan-Meier survival curves showed that the differences in survival by point score seen at 4 years were magnified at 10 years (FIGURE).Comment.We validated a mortality index that accurately stratified older adults into groups at varying risk for 10-year mortality.Extending the index from 4 to 10 years did not diminish the model discrimination (validation cohort, C statistics 0.817 vs 0.834; P=.35), suggesting that the risk factors important for 4-year mortality prediction are also important for 10-year mortality prediction.The model compares favorably with other mortality indexes that predict mortality beyond 7 years. 3 One limitation of the index is that it was developed and validated in a single, large, national study and should be validated on a separate population to assess generalizability.Patients identified by this index as having a high risk of 10-year mortality may be more likely to be harmed by preventive interventions with long lag times to benefit, whereas patients identified as having a low risk of 10-year mortality may be good candidates for such interventions.