Laboratory study finds modest weight increases after prolonged formalin fixation of placental tissue, indicating minimal impact on clinical weight diagnoses.
Key PointsBrief formalin fixation, 1 to 5 days, is known to result in a 5% to 7% increase in placental weight.We reweighed placentas originally weighed as part of clinical service and found a modest increase in placental weight.Five of 55 placentas received a different weight diagnosis, 3 higher, 2 lower.
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Sibert et al. (2026) studied this question.
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