Imaging findings for differentiating and predicting prognosis in undifferentiated pleomorphic sarcoma and myxofibrosarcoma

OBJECTIVE: This study aimed to examine the imaging findings of undifferentiated pleomorphic sarcoma (UPS) and myxofibrosarcoma (MFS) and identify a prognostic factor for recurrence. MATERIALS AND METHODS: F-fluorodeoxyglucose-PET/CT results were retrospectively examined and compared between the two diseases. RESULTS: /s, p < 0.01) were lower in UPS than in MFS. CT attenuation (37 vs. 22 Hounsfield Unit, p < 0.01) and maximum standardized uptake value (SUVmax) (15.6 vs. 5.2, p < 0.01) were greater in UPS than in MFS. Univariate analysis found that pathological diagnosis of UPS (hazard ratio: 15.6) and low or intermediate signal intensity on T2-weighted images (hazard ratio: 15.7) were predictors of recurrence. CONCLUSION: The signal intensity on T2-weighted images, ADC value, CT attenuation, and SUVmax were relevant imaging results for distinguishing UPS from MFS. The pathological diagnosis and signal intensity on T2-weighted images were prognostic indicators of recurrence.