An appraisal of the diagnostic value of the serological tests for toxoplasmosis

Investigations are cited to support the following conclusions: Trichomonas infection in man does not interfere with the dye test for toxoplasmosis. Trypanosoma gambiense and T. cruzi infection in man does not interfere with the dye test for toxoplasmosis. Infection with Salmonella typhi does not give rise to a positive complement-fixation test for toxoplasmosis using an egg antigen. Malaria in man does not interfere with the complement-fixation test for toxoplasmosis using an egg antigen. Inactivation at 56° C. for 30 minutes does not reduce the titre of the dye-test antibody in human serum; these antibodies, therefore, cannot be identified with propodin. The dye-test antibody for toxoplasmosis contained in sheep sera is inactivated at 56° C. and so cannot be identical with the human dye-test antibody. The reliability of the dye and complement-fixation tests in the diagnosis of toxoplasmosis is upheld.