Low-Dose Acyclovir and Acute Renal Failure

Letters and Corrections1 February 1988Low-Dose Acyclovir and Acute Renal FailureA. GIUSTINA, M.D., G. ROMANELLI, M.D., A. CIMINO, M.D., G. BRUNORI, M.D.A. GIUSTINA, M.D., G. ROMANELLI, M.D., A. CIMINO, M.D., G. BRUNORI, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-108-2-312_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: We report the case of a patient with severe acute renal failure associated with the administration of low-dose intravenous acyclovir.A 31-year-old man was hospitalized in July 1987 with swelling of the face, hands, and legs, nausea, abdominal cramps, scanty urine output, and acute hypertension. The patient had stage IV-B Hodgkin disease, diagnosed in June 1984. He was free from the disease and discontinued all treatment in July 1986, after remission was induced with four cycles of mustargen, vincristine, procarbazine, and prednisone (MOPP), followed by six cycles of doxorubicin, bleomycin, vinblastine, and dacarbazine (ABVD). The patient also...References1. JONESBEIER-HANRATTY PS. Acyclovir: neurologic and renal toxicity [Letter]. Ann Intern Med. 1986;104:892. LinkGoogle Scholar2. BEANAEPPLI BD. Adverse effects of high-dose intravenous acyclovir in ambulatory patients with acute herpes zoster. J Infect Dis. 1985;151:362-5. CrossrefMedlineGoogle Scholar3. BALFOUR H. Acyclovir therapy for herpes zoster: advantages and adverse effects. JAMA. 1986;255:387-8. CrossrefMedlineGoogle Scholar4. BREZISROSENEPSTEIN MSF. Acute renal failure. In: BRENNER BM, RECTOR FC, eds. The Kidney. Philadelphia; W.B. Saunders: 1986:735-99. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Universitá degli Studi di Brescia Spedali Civili; 25100 Brescia Italy PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byHIV-Associated Kidney DiseaseTowards Further Verification of Physiologically-Based Kidney Models: Predictability of the Effects of Urine-Flow and Urine-pH on Renal ClearanceThe drugs that mostly frequently induce acute kidney injury: a case − noncase study of a pharmacovigilance databaseResolution of acyclovir-associated neurotoxicity with the aid of improved clearance estimates using a Bayesian approach: A case report and review of the literatureA metabolic profiling analysis of the nephrotoxicity of acyclovir in rats using ultra performance liquid chromatography/mass spectrometryNéphrotoxicité des médicamentsAcute kidney injury due to acyclovirOral acyclovir induced acute renal failureThe Renal SystemDrug-induced crystal nephropathy: an updateAntiviral agentsChronic renal failure among HIV-1-infected patientsAntiretroviral therapy and the kidney: balancing benefit and risk in patients with HIV infectionAntiviral Drug-Induced NephrotoxicityDrug-induced renal failure: a focus on tubulointerstitial diseaseLargest dose of acyclovir inadvertently administered to a neonateDrug-Induced Renal Failure: Update on New Medications and Unique Mechanisms of NephrotoxicityAntiviral agentsCrystal-induced acute renal failureAntiviral agentsAcute renal failure in a child associated with acyclovirAcute Renal Failure and Neurotoxicity following Oral AcyclovirAcyclovir Neurotoxicity and Nephrotoxicity-The Role for HemodialysisDrug-Induced Renal DisordersAcyclovir-induced renal failure: course and risk factors 1 February 1988Volume 108, Issue 2Page: 312-312KeywordsAcute renal failureHodgkin lymphomaHypertensionInflammationNauseaProcarbazineUrine Issue Published: 1 February 1988 PDF downloadLoading ...