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June 1, 1976SIMULATION

Simulation of Biological Systems: Contraction of Skeletal Muscle

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Population

Skeletal muscle cross bridge models

Design

Review

Authors

DNDavid F NobleSandia National Laboratories California

Discussion

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Implication

Simulations distinguish cross-bridge model classes via targeted experiments; leaves open validation and cardiac translation.

Structured PICO

P
Population
Skeletal muscle cross bridge models
I
Intervention
Simulation of cross bridge models

Simulations of skeletal muscle cross bridge models can predict whole muscle behavior and guide experimental design to distinguish between competing mechanistic models.

Cite This Study

David F Noble (1976) studied this question.

synapsesocial.com/papers/6a8c136f9ac394ad33caca0bhttps://doi.org/10.1177/003754977602600604
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Tension development in highly stretched vertebrate muscle fibres1966 · 349 citations
  2. 2CROSS-BRIDGE PROPERTIES DERIVED FROM MUSCLE ISOTONIC VELOCITY TRANSIENTS1969 · 97 citations