A new palladium-catalyzed three-component coupling involving acylation/alkenylation of aryl iodide is reported. The reaction was carried out with readily available starting materials and gave the ortho-acylated styrene in moderate to good yields. Compared with previous Catellani–Lautens reactions, this reaction is the first example of introducing an acyl group at the ortho position of aryl iodides. The proposed Pd IV complex, generated via oxidative addition of the carboxylic anhydrides, is a key intermediate for this transformation.
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Zhou et al. (2015) studied this question.
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