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Without a trace? Recent advances in aliphatic radiofluorinations enabled by transition metals, specifically cobalt/salen and manganese/salen complexes, have been unveiled. These new approaches operate in a unique way which obviates the need for highly activated substrates for radiolabeling and offers a new synthetic strategy to prepare 18F-labeled radiotracers.
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Liang et al. (2014) studied this question.
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