Key result
Outcome-specific Charlson Comorbidity Indices showed good prognostic performance for inpatient mortality and morbidity (AUC >0.800) and performed better than the standard CCI and age-adjusted CCI.
Why the study?
Do outcome-specific Charlson Comorbidity Indices improve the prediction of inpatient mortality, cardiac, and renal morbidity compared to standard CCI in noncardiac surgery patients?
Population
356,425 noncardiac surgery patients from the 2010 and 2011 California State Inpatient Database
Comparison
Outcome-specific Charlson Comorbidity Indices… vs Standard Charlson Comorbidity Index and…
Design
Cohort
Follow-up
Inpatient
Authors
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May enhance preoperative risk assessment in noncardiac surgery; hypothesis-generating and requires prospective validation before practice change.
Cohort (n=356,425)
Yes
Do outcome-specific Charlson Comorbidity Indices improve the prediction of inpatient mortality, cardiac, and renal morbidity compared to standard CCI in noncardiac surgery patients?
Effect estimate: AUC >0.800
Outcome-specific Charlson Comorbidity Indices derived from administrative data provide superior prediction of inpatient mortality and morbidity following noncardiac surgery compared to standard indices.
Yoshan Moodley (2016) conducted a cohort in Noncardiac surgery (n=356,425). Outcome-specific Charlson Comorbidity Indices vs. Standard CCI and age-adjusted CCI (AACCI) was evaluated on Inpatient mortality, and cardiac and renal morbidity (AUC >0.800). Outcome-specific Charlson Comorbidity Indices showed good prognostic performance for inpatient mortality and morbidity (AUC >0.800) and performed better than the standard CCI and age-adjusted CCI.
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