Key result
A single ablation catheter technique successfully identified and closed all 74 residual gaps, demonstrating comparable efficacy and clinical outcomes to circular catheter mapping.
Why the study?
Does a single-catheter approach achieve comparable efficacy to a double-catheter approach for pulmonary vein antrum isolation in patients with paroxysmal atrial fibrillation?
RCT (n=110)
Does a single-catheter approach achieve comparable efficacy to a double-catheter approach for pulmonary vein antrum isolation in patients with paroxysmal atrial fibrillation?
A single-catheter technique is feasible and as effective as using a circular mapping catheter for localizing and closing residual gaps during pulmonary vein isolation for paroxysmal AF.
Supports single-catheter PVI for paroxysmal AF; extends RCT evidence for simplified ablation workflows.
OBJECTIVES: The present study was designed to investigate the feasibility and efficacy of single ablation catheter for complete circumferential pulmonary vein antrum (PVA) isolation. BACKGROUND: Complete isolation of pulmonary veins is the mainstay for atrial fibrillation (AF) ablation. This is usually performed under the guidance of a circular catheter. METHODS: One hundred and ten consecutive patients with paroxysmal AF were prospectively randomized into two groups: single-catheter approach (group 1) and double-catheter approach (group 2). After performing initial circumferential lesions, residual gaps were mapped and closed with single ablation catheter in group 1 or guided by a circular mapping catheter in group 2 using an electroanatomic mapping system (CARTO XP, Biosense-Webster Inc., Diamond Bar, CA, USA). RESULTS: Complete bilateral PVA isolation was achieved in 22 of the 110 patients after initial ablation. All residual gaps could be correctly identified by activation mapping using single ablation catheter. The distribution of these residual gaps was asymmetric. In group 1, 25 gaps along the right PVA lesions and 49 gaps along the left PVA lesions were identified. All the residual gaps were closed with single-catheter approach. In group 2, 28 gaps on the right side and 53 gaps on the left side were identified using a circular catheter and closed with further ablations. The procedure data and clinical outcomes between the two groups were comparable. CONCLUSIONS: Single ablation catheter technique is feasible and as effective as circular catheter mapping in localizing the residual gaps for PVA isolation during ablation of paroxysmal AF.
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Dong et al. (2008) conducted an RCT in Paroxysmal atrial fibrillation (n=110). Single-catheter approach (single ablation catheter) vs. Double-catheter approach (guided by a circular mapping catheter) was evaluated on Identification and closure of residual gaps, procedure data, and clinical outcomes. A single ablation catheter technique successfully identified and closed all 74 residual gaps, demonstrating comparable efficacy and clinical outcomes to circular catheter mapping.
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