Key result
Delaying cardiac catheterization 3-8 weeks after an upper respiratory infection yielded perioperative respiratory adverse event rates comparable to children without URI (OR 1.11; 95% CI 0.64-1.91).
Why the study?
The study aimed to evaluate anesthesia timing and risk factors for perioperative respiratory adverse events in children undergoing therapeutic cardiac catheterization after an upper respiratory tract infection.
Does delaying therapeutic cardiac catheterization by at least two weeks after an upper respiratory infection reduce perioperative respiratory adverse events in children?
Observational (n=332)
Does delaying therapeutic cardiac catheterization by at least two weeks after an upper respiratory infection reduce perioperative respiratory adverse events in children?
Answers are grounded in this paper and cite their sources.
Delaying elective therapeutic cardiac catheterization by at least two weeks after an upper respiratory infection in children minimizes the risk of perioperative respiratory adverse events.
BACKGROUND: We aimed to analyze anesthesia timing and perioperative respiratory adverse event (PRAE) risk factors in children undergoing therapeutic cardiac catheterization after upper respiratory tract infection (URI). METHODS: We prospectively included children for elective therapeutic cardiac catheterization. Parents or legal guardians were asked to complete a questionnaire on the child's demographics, tobacco exposure, and URI symptoms. PRAEs (laryngospasm, bronchospasm, coughing, airway secretion, airway obstruction, and oxygen desaturation) as well as details of anesthesia management were recorded. RESULTS: Of 332 children, 201 had a history of URI in the preceding eight weeks. The occurrence rate of PRAEs in children with URI≤two weeks reached the highest proportion, which was higher than that in children without URI (66.3% vs. 46.6%, P=0.007). The overall incidence of PRAEs in children with URI in 3-8 weeks was significantly lower than that in children with URI in the recent ≤two weeks (49.0% vs. 66.3%, P=0.007), and similar to that in the control group (49.0% vs. 46.6%). Multivariate analysis showed association between PRAEs and type of congenital heart disease (CHD) (P<0.001), anesthesia timing (P=0.007), and age (P=0.021). Delayed schedule (two weeks after URI) minimized the risk of PRAEs to the level comparable to that observed in children without URI (OR, 1.11; 95% CI: 0.64-1.91; P=0.707). CONCLUSIONS: If treatment is not urgent, a pediatric patient at a high risk of PRAEs will be benefit from the postponement of an interventional operation by at least two weeks after URI.
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Zhang et al. (2020) conducted an observational in upper respiratory tract infection prior to therapeutic cardiac catheterization (n=332). Delayed schedule (3-8 weeks after URI) vs. No URI was evaluated on perioperative respiratory adverse events (PRAEs) (OR 1.11, 95% CI 0.64-1.91, p=0.707). Delaying cardiac catheterization 3-8 weeks after an upper respiratory infection yielded perioperative respiratory adverse event rates comparable to children without URI (OR 1.11; 95% CI 0.64-1.91).
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