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Series of triphenylmethane and xanthene dyes were found to be effective as inducers of respiration-deficient mutation in yeast. The quantitative difference in the mutagenic effect appeared to be in close relationship to the chemical structure of the respective dyes. This survey may provide a useful clue for elucidation of the mechanism of mutagenic induction.
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Susumu Nagai (1959) studied this question.
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