Key result
Duration of ventilator weaning (OR 0.813) and age significantly influenced the success of fast-track extubation within four hours in post cardiac surgery patients.
Why the study?
What factors affect the success rate of early extubation in post-cardiac surgery patients admitted to a PACU?
Observational (n=145)
No
What factors affect the success rate of early extubation in post-cardiac surgery patients admitted to a PACU?
Odds Ratio: 0.813 (95% CI 0.698–0.928)
p-value: p=<0.001
In post-cardiac surgery patients, older age, higher surgical risk scores, longer bypass times, and inotrope use are significant predictors of failure to achieve early extubation.
For a total of six months duration, we non-selectively included all cardiac surgery patients admitted through our new post-anaesthesia care unit (PACU). We studied how patients' profile, comorbidities and operative data affect the success rate of extubation. 107 of the total 145 patients admitted to PACU were able to be extubated. However, only 79(54.5%) patients were able to be extubated within four hours. Within the success group, we found that age (OR = 0.912; 95% CI = 0.044-1.779) and duration of ventilator weaning (OR = 0.813; 95% CI = 0.698-0.928) significantly influenced the extubation time with p-value of 0.040 and <0.001 respectively. Within the failure group, age (HR = 1.061; 95% CI = 1.018-1.105), EUROscore II (HR = 2.303; 95% CI = 1.416-3.748), cardiopulmonary bypass time (HR = 1.015; CI 95% 1.005-1.025), aortic cross-clamp time (HR = 1.023; 95% CI = 1.010-1.037) and post-operative inotropic usage (HR = 2.892; 95% CI = 1.637-5.109) significantly affect failure of extubation with p-values of 0.005, 0.001, 0.004, 0.001 and <0.001 respectively.
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Tham et al. (2015) conducted an observational in Post cardiac surgery (n=145). Duration of ventilator weaning was evaluated on Successful extubation within four hours (OR 0.813, 95% CI 0.698-0.928, p=<0.001). Duration of ventilator weaning (OR 0.813) and age significantly influenced the success of fast-track extubation within four hours in post cardiac surgery patients.
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