DNA-topoisomerases are sophisticated enzymes controlling DNA topology in cells. A lot of new data concerning the structure and functions of topoisomerases was published recently. In this review authors discuss basic features of the different types of topoisomerases with respect to catalytic mechanism and focus at the involvement of topoisomerases in various DNA-related cellular processes, such as replication, transcription, recombination, chromatin condensation and daughter chromatides partitioning.
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Ghilarov et al. (2012) studied this question.
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