Key result
A prediction model for postoperative gastrointestinal complications after aortic arch surgery was developed based on six predictors, with GICs occurring in 157 of 3063 patients.
Why the study?
Postoperative gastrointestinal complications are potentially fatal after aortic arch surgery, prompting the need to construct a prediction model.
What are the predictors of postoperative gastrointestinal complications in patients undergoing aortic arch surgery?
Cohort (n=3,063)
No
What are the predictors of postoperative gastrointestinal complications in patients undergoing aortic arch surgery?
A newly developed nomogram based on six intraoperative and preoperative factors can predict the risk of gastrointestinal complications after aortic arch surgery.
May inform perioperative risk stratification in aortic arch surgery; hypothesis-generating and requires prospective validation.
BACKGROUND: Postoperative gastrointestinal complications (GICs) were potentially fatal to patients who underwent aortic arch surgery. The aim of this study was to construct a prediction model of GICs. METHODS: We retrospectively studied the medical records of 3063 patients who underwent aortic arch surgery. Patients were randomly divided into derivation and validation cohorts at a ratio of 4:1. A nomogram was constructed in the derivation cohort. RESULTS: A total of 157 patients with GICs were identified. In the derivation cohort, multivariate analysis identified six predictors of GICs including hypertension, ASA classification, preinduction MAP, aortic cross-clamp time, CPB time, and intraoperative transfusion of red blood cells. Compared with the patients without GICs, the patients with GICs had higher mortality, and longer ICU and hospital stays. We also divided the patients into four intervals according to the risk of GICs. CONCLUSIONS: This study developed a reliable prediction model of GICs after aortic arch surgery. This prediction model had been well verified in our research centre, and further external verification was required before it can be recommended for clinical application.
No takes yet. Share an insight, caveat, or question.
Liu et al. (2023) conducted a cohort in Aortic arch surgery (n=3,063). Risk factors (hypertension, ASA classification, preinduction MAP, aortic cross-clamp time, CPB time, intraoperative transfusion of red blood cells) vs. Patients without the risk factors was evaluated on Postoperative gastrointestinal complications (GICs). A prediction model for postoperative gastrointestinal complications after aortic arch surgery was developed based on six predictors, with GICs occurring in 157 of 3063 patients.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: