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Studies were made on the effects of baicalein (5,6,7‐trihydroxyflavone) on leukotriene C4 (LTC4) biosynthesis by calcium ionophore A 23187 in human lymphocytes. Baicalein inhibited calcium ionophore‐induced LTC4 biosynthesis in human lymphocytes. The concentration of baicalein required for 50% inhibition (IC50) of LTC4 formation was 4.3 × 10−7 M.
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Kimura et al. (1987) studied this question.
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