Bleeding Tendency in Uremia

ALTHOUGH abnormal bleeding has been known to occur as a complication of renal failure at least since the time of Bright (1827) surprisingly little attention has been paid to this problem. A recent monograph on coagulation1 assigns four sentences to bleeding in uremia. As mentioned by Larrain,2 a recent comprehensive review3 on the management of acute renal failure does not mention bleeding as a possible complication.Riesman,4 writing in 1907, appears to have been the first to recognize renal disease as the cause of a hemorrhagic diathesis. Other authors believed that the hemorrhagic diathesis caused the renal disease, or resulted . . .