Cryostat sections of 10 malignant human tumours of various types strongly adsorbed erythrocytes sensitized with IgG antibodies Normal spleen and lymph nodes showed medium Strong and thymus weak reactions. The receptors in tissue have affinity for the Fc‐portion of Ig, and (phospho)lipids are common consituents. An antiserum to a lymphoma inhibited receptor activity of all tissues. Spleen and tumour tissue removed this inhibiting activity. Tentatively, the malignant tissue seems to carry membrane receptor(s) similar in nature to receptor(s) on B lymphocytes.
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Tönder et al. (1973) studied this question.
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