The tabby locus (Ta) in the mouse: its site of action in tail and body skin

SUMMARY By means of grafting skin in which the epidermis of one genotype was combined with dermis of another to a nude host, we have shown that the effect of the mutant at the tabby (Ta) locus on follicle initiation in tail skin was not confined to either the epidermis or the dermis, that the effect ofTaon the morphology of body hairs was determined by the epidermis but that the close proximity of epidermis of a different genotype also affected body hair morphology.