Key result
A severe subarachnoid hemorrhage induced Takotsubo cardiomyopathy and acute myocardial infarction in a 64-year-old female, highlighting the importance of considering brain bleeds in patients presenting with AMI.
Why the study?
Intracranial bleeds can lead to cardiac complications, prompting exploration into how cerebral hemorrhage triggers apical ballooning syndrome and highlighting the need to consider brain bleeds when acute myocardial infarction presents.
Case Report (n=1)
No
Answers are grounded in this paper and cite their sources.
This case highlights the importance of considering intracranial hemorrhage in the differential diagnosis for patients presenting with acute myocardial infarction and neurological symptoms, as heparin treatment is contraindicated.
Intracranial bleeds, such as subarachnoid hemorrhage, carry high morbidity and mortality rates. Often intracranial hemorrhages result in debilitating residual neurological symptoms but can be so extensive that cardiac complications can also be seen. We present a rare case of a patient who was found to have a subarachnoid hemorrhage that incited the development of Takotsubo cardiomyopathy, which subsequently progressed to an acute myocardial infarction. The aim of this case report is to explore the underlying pathophysiology of how cerebral hemorrhage can result in apical ballooning of the left ventricle through various mechanisms including sympathetic-induced surge in catecholamines and neurogenic damage to the myocardium. We also intend to highlight the importance for clinicians to consider brain bleeds in the differential diagnosis when a patient presents with an acute myocardial infarction as treatment with heparin is generally contraindicated.
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Imburgio et al. (2022) conducted a case report in Subarachnoid hemorrhage and Takotsubo cardiomyopathy (n=1). Subarachnoid hemorrhage was evaluated. A severe subarachnoid hemorrhage induced Takotsubo cardiomyopathy and acute myocardial infarction in a 64-year-old female, highlighting the importance of considering brain bleeds in patients presenting with AMI.
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