Why the study?
Does famotidine induce thrombocytopenia in neurosurgical patients?
Does famotidine induce thrombocytopenia in neurosurgical patients?
Famotidine use in neurosurgical patients is associated with a significantly higher incidence of thrombocytopenia compared to no H2 antagonist use, suggesting alternative gastrointestinal prophylaxis may be preferable.
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Famotidine was associated with thrombocytopenia in neurosurgical patients; leaves open causality and requires prospective confirmation before changing prophylaxis.
Ecker et al. (2004) studied this question.
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