Relationship between the Level of Fibrinogen and the Signal Density on Brain Computed Tomography in the Chronic Subdural Hematoma

Objective: The purpose of this study was to evaluate the relationship between fibrinogen levels and computed tomography (CT) findings in patients who had chronic subdural hematomas (CSDHs). Methods: The study group was composed of 12 consecutive patients who had CSDH between January and December 2006. Patients with CSDH were divided on the basis of CT findings into group A (layering, mixed type) and group B (low, iso type). We performed surgery and obtained a sample from the subdural hematoma for measurement of the concentration of fibrinogen. Results: The mean level of fibrinogen was 57.3 mg/dL in group A, and in <25 mg/dL group B. The concentration of fibrinogen was significantly higher in the layering and mixed type group than in the low and iso type group (p=0.003). Conclusion: The layering, mixed type of CSDH demonstrated higher concentrations of fibrinogen in subdural hematomas than in low, iso type patients. (J Kor Neurotraumatol Soc 2010;6:43-47)