A family of chiral diphosphanes with systematically tunable electronic and steric properties have been used in the asymmetric hydrogenation of β-aryl ketoesters with excellent ee values (up to 99.8 %) by taking advantage of remarkable 4,4′-substituent effects on binap. These highly enantioselective Ru catalysts have also been effectively immobilized in room-temperature ionic liquids (RTIL).
No takes yet. Share an insight, caveat, or question.
Hu et al. (2004) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: