In Response:

In Response: would like to thank Profe- Jorge Albores-Saavedra for the comments that he made our publication.3 2 tumors papillary thyroid carcinoma with features that he described to have characteristics in com- with some of the tumors descri- by Asioli et al.3 hobnail in oncocytic neoplasms have been,1,4,5,7,8 that such usually have a more aggres- biologic behavior is important to the clinicopathologic findings in our report.3 other tumors such as tall-cell carci- may have oncocytic features behave more aggressively than papillary thyroid carcinomas,7 other tumors with oncocytic such as Warthin-like papil- thyroid carcinomas behave more typical papillary thyroid carcino-.2, molecular changes such p53 overexpression and BRAF that we described may be parameters to explain the aggressive behavior of the tumors our series. In addition, changes in orientation with loss of polarity possibly alteration in specific gly-6 contribute to the propensity to metastasize to sites usually encountered with typical thyroid carcinomas