Why the study?
The study was conducted to quantify the bias of shear wave speed measurements in a viscoelastic phantom across six ultrasound systems and compare them with transient elastography and magnetic resonance elastography.
Does the ultrasound system used affect the shear wave speed measurement in a viscoelastic phantom compared to transient elastography and magnetic resonance elastography?
Does the ultrasound system used affect the shear wave speed measurement in a viscoelastic phantom compared to transient elastography and magnetic resonance elastography?
Shear wave speed measurements in a viscoelastic phantom vary significantly across different ultrasound elastography systems and are generally higher than those obtained with transient elastography and magnetic resonance elastography.
Answers are grounded in this paper and cite their sources.
SWE SWS varies by system and exceeds MRE/TE in phantoms; leaves open standardization before clinical use.
PURPOSE: To quantify the bias of shear wave speed (SWS) measurements in a viscoelastic phantom across six different ultrasound (US) systems and to compare the SWS with those from transient elastography (TE) and magnetic resonance elastography (MRE). METHODS: A viscoelastic phantom of stiffness representing fibrotic liver or healthy thyroid was measured with nine (linear probe) and 10 (convex probe) modes of six different US-based shear wave elastography (SWE) systems using linear and convex probes. SWS measurements of three regions of interest were repeated thrice at two focal depths, coupling the probe to the phantom using a jig. An MRE system using three motion-encoding gradient frequencies of 60, 90, and 120 Hz and TE were also used to measure the stiffness of the phantom. RESULTS: The SWS from different SWE systems had mean coefficients of variation of 9.0-9.2% and 5.4-5.6% with linear and convex probes, respectively, in viscoelastic phantom measurement. The focal depth was a less significant source of SWS variability than the system. The total average SWS obtained with US-SWE systems was 19.9% higher than that obtained with MRE at 60 Hz, which is commonly used in clinical practice, and 31.5% higher than that obtained with TE using the M probe. CONCLUSIONS: Despite the measurement biases associated with the SWE systems, biases were not necessarily consistent, and they changed with the probes used and depth measured. The SWS of the viscoelastic phantom obtained using different modalities increased according to the shear wave frequency used.
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A 2022 study studied this question.
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