Why the study?
Does procaine added to cardioplegia reduce postischemic ventricular fibrillation in patients undergoing CABG?
Population
56 patients scheduled for coronary artery bypass grafting (CABG)
Comparison
St. Thomas' Hospital cardioplegic solution II… vs St. Thomas' Hospital cardioplegic solution II…
Design
RCT, randomized, double-blind
Follow-up
first day after surgery
Authors
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Supports adding procaine to cardioplegia in CABG; confirms efficacy for preventing defibrillation-requiring VF.
Does procaine added to cardioplegia reduce postischemic ventricular fibrillation in patients undergoing CABG?
Adding 1 mM procaine to cardioplegia significantly reduces the incidence of postischemic ventricular fibrillation requiring DC shock after aortic declamping in CABG surgery.
Sellevold et al. (1995) studied this question.
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