Population
12 patients undergoing routine cardiac and cardiopulmonary bypass surgery
Design
Cohort
Follow-up
during surgery
Authors
Loading...
Pericardial coagulation activation during CPB is hypothesis-generating; leaves open localized factor VIIa targeting pending prospective trials.
Appreciable activation of factor VII occurs in the pericardium during cardiopulmonary bypass surgery, suggesting it should be a target for localized anticoagulant strategies.
Philippou et al. (1999) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: