Proceedings of the Australasian Society of Clinical and Experimental Pharmacologists

The development of the prejunctional receptor hypothesis. M.W. McCulloch, M.J. Rand and D. F. Story 2. Adrenoceptor‐ and cholinoceptor‐mediated modulation of transmitter release at the somatic neuromuscular junction. C. Raper 3. Conditions of operation of positive and negative feedback regulation of transmitter noradrenaline release. D.F. Story and I.C. Medgett 4. Failure of a receptor blockade–a pre‐ and post‐synaptic phenomenon. G.D.S. Hirst and T.O. Neild 5. Are radioligand assays useful for identification and characterization of prejunctional receptors? R.J. Summers and B. Jarrott 6. Prejunctional modulation of postganglionic cholinergic nerves. F. Mitchelson 7. Opiate receptor modulation of transmitter release. J.E. Olley* and A.L.A. Boura 8. Prejunctional receptors of human vascular sympathetic nerves. R.F. W. Moulds 9. Clinical implications of autonomic prejunctional receptors. J. Shaw 10. Correlations between the antihypertensive and haemodynamic effects of oxprenolol. R. Zacest, M.A. Robinson and L.L. Wilson 11. Comparison of long acting and short acting diuretics in mild essential hypertension. L.M.H. Wing, M.J. West, J.R. Graham and J.P. Chalmers 12. Effects on heart rate and blood pressure during graded exercise of beta adrenoceptor blocking drugs with and without intrinsic sympathomimetic activity (ISA) or ‘cardio‐selectivity’. G. Jennings, A. Bobik, P. Ashley, R. Newman, S. Ellet and P. Korner 13. Study of the effects of acute dosing with ac‐methyl dopa on reflex autonomic tachycardia. A.J. McLean, G. Jennings and P.I. Korner 14. A study of in vitro vasoactivity of C.S.I, and the clinical state of patients who have had a subarachnoid haemorrhage. R.F.W. Moulds, C. Mylonas, R. Medcalfand D. Brownbill 15. Retrospective survey of digoxin usage. C. Corallo and K. Raymond 16. Dihydroergotamine kinetics in patients with orthostatic hypotension. A. Bobik, H. Skews, G. Jennings, M. Esler and P.I. Korner 17. Effect of probenecid on clofibrate disposition in man. J.R. Veenendaal. P.M. Brook and P.J. Meffin 18. Pharmacokinetics in human malnutrition. N. Buchanan 19. Impairment of an hepatic protective mechanism in man by food ingestion. A.J. McLean, C. Isbister, A. Bobik and F.J. Dudley 20. Carbamazepine monotherapy in epileptic patients. G.W. Mihaly and F.J.E. Vajda 21. Simultaneous determination of aspirin, salicyclic acid, salicyluric acid and gentisic acid in plasma by HPLC. R.H. Rumble and M.S. Roberts 22. Association between angiotensin conversion and prostacyclin release in isolated mesenteric vasculature of rats. G.J. Dusting and E.M. Mullins 23. Prostacyclin inhibits contractions of the rat isolated descending colon in response to field stimulation. I.R.N. Relf and A.L.A. Boura 24. Bradykinin induced spasm of the human umbilical vein is mediated via activation of phospholipase‐A and potentiated by cooling. A.L.A. Boura, A.S.C. Sandford, R.J. McRae and W.A.W. Walters 25. L‐Tryptophan‐induced depression of α‐adrenoceptor mediated vascular responses in the rat. P.L. Nolan and J.W. Caygill 26. Evidence against a physiological role of presynaptic alpha adrenoceptors in heart. J.A. Angus and P.I. Korner 27. The effect of DOCA hypertension on responses of the rat tail artery to potassium chloride and electrical stimulation. M.G. Venning and I.S. de la Lande 28. A possible histaminergic component of the clonidine withdrawal syndrome in the rat. S.J. Lewis, M.R. Fennessy and D.A. Taylor 29. Clonidine withdrawal syndrome and endogenous biogenic amines. D.A. Taylor, S.J. Lewis and M.R. Fennessy 30. The effects of sub‐acute L‐DOPA treatment of mice on L‐DOPA‐induced hyperactivity. O. Jenkins, R. Bailey, E. Crisp and D.M. Jackson 31. Chronic L‐DOPA pretreatment of mice: production of dopamine receptor supersensitivity? R. Bailey, E. Crisp, D.M. Jackson and O. Jenkins 32. Accumulation of α‐methylated phenolamines in rat brain after chronic administration of a‐methyltyrosine. P.H. Duffield, D.F.H. Dougan, D.N. Wade and A.M. Duffield 33. Effect of unilateral lesions on octopamine and tyramine concentrations in rat striatum. D.F.H. Dougan, P.H. Duffield, D.N. Wade, A.M. Duffield and G. Paxinos 34. Effect of surgical denervation on α1 and α2‐adrenoceptors in rat cerebral cortex. M.J. Morris, J.L. Elghozi, J.P. Dausse and P. Meyer 35. Localization of |3H|clonidine binding sites in membranes prepared from guinea pig renal cortex. G. McPherson and R.J. Summers 36. Characterization of (3H)cIonidine binding sites in membranes prepared from guinea pig spleen. R.J. Summers and G. McPherson 37. Alpha‐adrenergic receptors modulate agonist affinity for beta‐receptors in rat kidney membranes. E.A. Woodcock and C.A. Olsson 38. Pentobarbitone enhancement of GABA binding. M. Willow and G.A.R. Johnston 39. Stress induced changes in Leucine‐enkephalin binding and plasma corticosterone in mice. M.J. Christie, P. Trisdikoon, J. Eross and G.B. Chesher 40. Duration of the analgesic effects of some opiate‐like peptides following intracerebroven‐tricular (i.c.v.) administration in the rat. M.J. Quinn and M.R. Fennessy 41. Relationship between δ9‐tetrahydrocannabinol (δ9‐THC) withdrawal behaviour and brain regional levels of histamine (HA) in the rat. A.J.M. Verberne, D.A. Taylor, S.J. Lewis and M.R. Fennessy 42. Long‐term effects of a single dose of haloperidol or thioridazine on schedule induced drinking. G. Singer 44. Effect of o‐methylflavinantine on contractions of the guinea‐pig longitudinal muscle induced by co‐axial electrical stimulation. R. Ansa‐Asamoah and G.A. Starmer 45. Do endogenous purine nucleosides modulate the release of acetylcholine at the mammalian neuromuscular junction? I. Spence 46. Effect of adrenaline on transmitter noradrenaline release. H. Majewski, M.W. McCulIoch, M.J. Rand and D.F. Story 47. Effects of tetrodotoxin on release of noradrenaline by nicotine in rabbit atria. C. Sarantos‐Laska, M.W. McCulloch, D.F. Story and M.J. Rand 48. The effect of ventilatory gas composition on arachidonic acid metabolism in isolated perfused guinea‐pig lungs. V. Iwanov, J. Staszewska‐Barczak and G.J. Dusting 49. An isolated perfused adrenal preparation for studying adrenal catecholamine secretion. A.R. Collett and D.F. Story 50. Inhibition of nerve‐mediated contractions in isolated guinea‐pig ileum by 1‐methyliso‐guanosine, a novel purine from a sponge. D. Jamieson and P. Davis 53. β‐Adrenoceptors and catecholamine‐induced responses of human and porcine peripheral lung strip: Effects of uptake inhibitors. R.G. Goldie and G.M. Ellis 54. Uptake and release of N‐methyl‐D‐aspartate by rat brain slices. J.H. Skerritt and G.A.R. Johnston 62. Receptor binding assay for detection of endogenous opioids. P.M. Lewis and J.E. Olley 63. Prospective drug utilization study of antibiotics based on blood level assays. A. Saunders and K. Raymond 57. The pharmacokinetics of chlorbutol. C. Tung, G.G. Graham, D.N. Wade and K.M. Williams 58. Effect of desmethylimipramine on the anorectic activity and tissue distribution of chlorphentermine in rats. R.F. Minchin, K.F. Ilett and B.W. Madsen 59. Effects of a new monoamine oxidase‐A selective inhibitor (MD780515) on amine metabolism in the small intestine. K.F. Ilett, C.F. George and D.S. Davies 60. Hepatic elimination of sodium valproate (SV). F.J.E. Vajda, A.W. Marshall, G.W. Mihaly, R.A. Smallwood, J. Baldas and J. Phillips 61. A sensitive method for measurement of catecholamines and their metabolites in extracts of small brain areas. P.R. Rowe, R.J. Summers and P.M. Beart 62. Receptor binding assay for detection of endogenous opioi