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Cardiac allograft vasculopathy remains a leading cause of late mortality after heart transplantation with limited medical treatment options beyond risk factor modification, immunosuppression, and retransplantation.
Cardiac allograft vasculopathy is one of the leading causes of death following the first 5 years after orthotopic heart transplantation along with late graft failure, likely secondary to undiagnosed CAV. Currently there is no single medical treatment available for this condition except modification of risk factors and immunosuppression. Retrasplantation remains the hope for this entity with some limitations.
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Rama Bindu Manchikalapudi (2017) studied this question.
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