A new chloroxylenol preparation (DC) containing ethylenediamine tetraacetic acid (EDTA). has been shown to be an effective bactericidal agent against various Gram positive and Gram negative bacteria. It possessed significant and rapid activity against two strains of Pseudomonas aeruginosa as well as against chlorhexidine‐and chloroxylenol‐resistant derivatives of these strains. DC showed high activity at 20° and 30 °C, and (unlike chlorhexidine) when prepared in hard water or when used in the presence of organic matter. Repeated challenge testing at 20 °C of DC (but not of chloroxylenol) with Ps. aeuruginosa indicated that contamination of DC will not prove to be a problem in practice and that the activity of solutions will be retained during storage.
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Russell et al. (1977) studied this question.
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