Large outbreaks of hepatitis E virus (HEV) infection were first recognized as a distinct clinical entity in the early 1980s.1,2 Outbreaks continue and involve thousands of patients in certain geographic regions of the world, including the Indian subcontinent, northwest China, and the Central Asian Republics (the former Soviet Union) — areas where HEV infection is endemic.3 HEV is transmitted predominantly through the fecal–oral route, and most reported outbreaks of infection have been related to the consumption of fecally contaminated drinking water; person-to-person transmission of the disease appears to be uncommon. There is a high attack rate in adults and . . .
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Krzysztof Krawczynski (2007) studied this question.
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