Why the study?
Does systemic anticoagulant infusion resolve superior mesenteric vein thrombosis associated with hormonal contraceptive use?
Does systemic anticoagulant infusion resolve superior mesenteric vein thrombosis associated with hormonal contraceptive use?
Early diagnosis and immediate systemic anticoagulant therapy can effectively resolve superior mesenteric vein thrombosis associated with hormonal contraceptive use, potentially preventing intestinal infarction.
Anticoagulant resolution seen in one contraceptive-related SMVT case; leaves open need for controlled data before wider use.
A 44-year-old woman was admitted with a 7-day history of lower abdominal pain and nausea. Physical examination demonstrated tenderness in the lower abdomen without signs of peritonitis. There were no specific findings in the laboratory evaluation. She had a history of dysmenorrhea for 15 years and was taking a combined hormonal contraceptive containing 0.02 mg ethinyl estradiol and 3 mg drospirenone for 19 months. Contrast-enhanced computed tomography showed superior mesenteric vein thrombosis (SMVT). Systemic anticoagulant infusion was immediately administered and the symptoms disappeared within 2 days. The thrombus disappeared after 3 months. This case report suggests that early diagnosis of SMVT and immediate systemic anticoagulant therapy may reduce the rate of intestinal infarction.
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Nobuatsu KOYAMA (2016) studied this question.
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