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February 1, 1985Antimicrobial Agents and Chemotherapy

Development of plasmid-mediated resistance in Vibrio cholerae during treatment with trimethoprim-sulfamethoxazole

M.J. Dupont Michèle Jouvenot G. Couetdic Y Michel-Briand

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Abstract

The persistence of Vibrio cholerae, biotype el tor, in a patient treated with trimethoprim-sulfamethoxazole was due to the acquisition of a conjugative resistance plasmid. The plasmid, with a molecular size of 72 megadaltons, belonged to incompatibility group 6-C and conferred resistance to ampicillin, chloramphenicol, sulfonamide, and trimethoprim.

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Dupont et al. (1985) studied this question.

synapsesocial.com/papers/6a8d01239cd95633742f089c https://doi.org/10.1128/aac.27.2.280

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