High-Risk Nonmelanoma Skin Cancers

background. Some nonmelanoma skin cancers are at high risk to recur after treatment, metastasize, and cause death. objective. To provide profiles of nonmelanoma skin cancers that are at high risk of aggressive behavior. methods. Review the studies of nonmelanoma skin cancers associated with calculated recurrences after treatment, metastasis, and patient mortality. results. Profiles have been developed for nonmelanoma skin cancers considered to be at high risk. conclusions. Physician awareness of nonmelanoma skin cancers that can behave aggressively is increased by establishing high-risk profiles for these cancers.