W hen considering chronic opioid therapy (COT) for chronic noncancer pain, it has been proposed that it is prudent to contemplate 4 questions which may be useful and influence medical decision making (1): 1. What is the conventional practice? 2. Are there reasonable alternatives to COT? 3. What is the risk of adverse events? 4. Is the patient likely to be a responsible drug-taker?
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Howard S. Smith (2012) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: