Answers are grounded in this paper and cite their sources.
Catch and release: A hairpin-shaped sense strand (red)/antisense strand (blue) siRNA probe was designed to be activated by a trigger RNA molecule. In the presence of the trigger RNA, clear OFF-to-ON switching of RNAi activity was observed with high sequence dependency (see schematic illustration).
No takes yet. Share an insight, caveat, or question.
Masu et al. (2009) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: